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1

Reactive microglia in aging and dementia: an immunohistochemical study of postmortem human brain tissue

Margit Overmyer, Seppo Helisalmi, Hilkka Soininen, Markku Laakso, Paavo Riekkinen Sr., I. Alafuzoff

Journal:

Acta Neuropathologica

Year:

1999

Language:

english

File:

PDF, 137 KB

english, 1999

2

Induced expression of neurotrophins in transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine

M. Reeben, J. Arbatova, J. Palgi, R. Miettinen, M. Halmekytö, L. Alhonen, J. Jänne, P. Riekkinen Sr., M. Saarma

Journal:

Journal of Neuroscience Research

Year:

1996

Language:

english

File:

PDF, 749 KB

english, 1996

3

The role of beta-endorphin and related peptides in the pathogenesis and treatment of Alzheimer's disease

Professor Paavo Riekkinen Sr, Eeva-Liisa Helkala, Jukka Jolkkonen, Paavo Riekkinen Jr., Hilkka Soininen

Journal:

Drug Development Research

Year:

1990

Language:

english

File:

PDF, 391 KB

english, 1990

4

Effects of single and repeated administration of vigabatrin on the performance of rats in a 5-choice serial reaction time task

Maria Mazurkiewicz, Jouni Sirviö, Paavo Riekkinen Sr.

Journal:

Epilepsy Research

Year:

1992

Language:

english

File:

PDF, 793 KB

english, 1992

5

Effects of single and repeated administration of vigabatrin on the performance of non-epileptic rats in a delayed non-matching to position task

Maria Mazurkiewicz, Jouni Sirviö, Paavo Riekkinen Sr.

Journal:

Epilepsy Research

Year:

1993

Language:

english

File:

PDF, 817 KB

english, 1993

6

Systemic Administration of Atipamezole, a Selective Antagonist of Alpha-2 Adrenoceptors, Facilitates Behavioural Activity but does not Influence Short-term or Long-term Memory in Trimethyltin-intoxicated and Control Rats

M Niittykoski, R Lappalainen, J Jolkkonen, A Haapalinna, P Riekkinen Sr, J Sirviö

Journal:

Neuroscience & Biobehavioral Reviews

Year:

1998

Language:

english

File:

PDF, 1.14 MB

english, 1998

7

Long-term cognitive and EEG effects of tiagabine in drug-resistant partial epilepsy

R. Kälviäinen, M. Äikiä, E. Mervaala, A.M. Saukkonen, A. Pitkänen, P.J. Riekkinen Sr.

Journal:

Epilepsy Research

Year:

1996

Language:

english

File:

PDF, 499 KB

english, 1996

8

Predictors of seizure outcome in newly diagnosed partial epilepsy: memory performance as a prognostic factor

Marja Äikiä, Reetta Kälviäinen, Esa Mervaala, Paavo J. Riekkinen Sr

Journal:

Epilepsy Research

Year:

1999

Language:

english

File:

PDF, 88 KB

english, 1999

9

The relationship of cerebrospinal fluid monoamine metabolites with clinical response to tetrahydroaminoacridine in patients with Alzheimer's disease

K. Alhainen, E. -L. Helkala, K. Reinikainen, P. Riekkinen Sr

Journal:

Journal of Neural Transmission - Parkinson's Disease and Dementia Section

Year:

1993

Language:

english

File:

PDF, 561 KB

english, 1993

10

Additive deficits in the choice accuracy of rats in the delayed non-matching to position task after cholinolytics and serotonergic lesions are non-mnemonic in nature

S. Ruotsalainen, Ewen MacDonald, Riitta Miettinen, Tarja Puumala, Paavo Riekkinen Sr., Jouni Sirviö

Journal:

Psychopharmacology

Year:

1997

Language:

english

File:

PDF, 363 KB

english, 1997

11

THA disrupts mismatch negativity in Alzheimer disease

P. Riekkinen Jr., A. Pääkkönen, Jari Karhu, Juhani Partanen, Hilkka Soininen, Mikko Laakso, P. Riekkinen Sr., P. Riekkinen Sr.

Journal:

Psychopharmacology

Year:

1997

Language:

english

File:

PDF, 250 KB

english, 1997

12

Diagnostic accuracy of alzheimer’s disease: A neuropathological study

O. Kosunen, H. Soininen, L. Paljärvi, O. Heinonen, S. Talasniemi, P. J. Riekkinen Sr

Journal:

Acta Neuropathologica

Year:

1996

Language:

english

File:

PDF, 1.91 MB

english, 1996

13

Pitfalls in the quantitative estimation of β-amyloid immunoreactivity in human brain tissue

M. Kraszpulski, Hilkka Soininen, Paavo Riekkinen Sr., Irina Alafuzoff

Journal:

Histochemistry and Cell Biology

Year:

1998

Language:

english

File:

PDF, 361 KB

english, 1998

14

MRI volumetry and T2 relaxometry of the amygdala in newly diagnosed and chronic temporal lobe epilepsy

Reetta Kälviäinen, Tuuli Salmenperä, Kaarina Partanen, Pauli Vainio, Paavo Riekkinen Sr, Asla Pitkänen

Journal:

Epilepsy Research

Year:

1997

Language:

english

File:

PDF, 240 KB

english, 1997

15

Elevated Seizure Threshold and Impaired Spatial Learning in Transgenic Mice with Putrescine Overproduction in the Brain

T. Halonen, J. Sivenius, R. Miettinen, M. Halmekytö, R. Kauppinen, R. Sinervirta, L. Alakuijala, L. Alhonen, E. MacDonald, J. Jänne, P. J. Riekkinen Sr

Journal:

European Journal of Neuroscience

Year:

1993

Language:

english

File:

PDF, 1.41 MB

english, 1993

16

NADPH Diaphorase-Containing Nonpyramidal Cells in the Rat Hippocampus Exhibit Differential Sensitivity to Kainic Acid

R. Miettinen, T. Kotti, T. Halonen, P. Riekkinen Sr

Journal:

European Journal of Neuroscience

Year:

1995

Language:

english

File:

PDF, 1.29 MB

english, 1995

17

The Calretinin-containing Mossy Cells Survive Excitotoxic Insult in the Gerbil Dentate Gyrus. Comparison of Excitotoxicity-induced Neuropathological Changes in the Gerbil and Rat

T. Kotti, T. Tapiola, P. J. Riekkinen Sr, R. Miettinen

Journal:

European Journal of Neuroscience

Year:

1996

Language:

english

File:

PDF, 3.46 MB

english, 1996

18

Second European Stroke Prevention Study: antiplatelet therapy is effective regardless of age

J. Sivenius, L. Cunha, H.-C. Diener, C. Forbes, M. Laakso, A. Lowenthal, P. Smets, P. Riekkinen Sr, for the ESPS2 Working Group

Journal:

Acta Neurologica Scandinavica

Year:

1999

Language:

english

File:

PDF, 504 KB

english, 1999

19

Linkage disequilibrium in the 13q12 region in Finnish late onset Alzheimer's disease patients

Hiltunen, Mikko, Mannermaa, Arto, Koivisto, Anne Maria, Lehtovirta, Maarit, Helisalmi, Seppo, Ryynänen, Markku, Sr, Paavo Riekkinen, Soininen, Hilkka

Journal:

European Journal of Human Genetics

Year:

1999

Language:

english

File:

PDF, 221 KB

english, 1999

20

Coexistence of parvalbumin and GABA in nonpyramidal neurons of the rat entorhinal cortex

Maria Miettinen, Esa Koivisto, Paavo Riekkinen Sr., Riitta Miettinen

Journal:

Year:

1996

Language:

english

File:

PDF, 2.49 MB

english, 1996

21

Apolipoprotein E (apoE) levels in brains from Alzheimer disease patients and controls

T. Pirttilä, H. Soininen, O. Heinonen, T. Lehtimäki, N. Bogdanovic, L. Paljärvi, O. Kosunen, B. Winblad, P. Riekkinen Sr., H.M. Wisniewski, P.D. Mehta

Journal:

Year:

1996

Language:

english

File:

PDF, 640 KB

english, 1996

22

Effects of p-chlorophenylalanine and methysergide on the performance of a working memory task

Pekka Jäkälä, Jouni Sirviö, Paavo Riekkinen Jr., Paavo J. Riekkinen Sr.

Journal:

Pharmacology Biochemistry and Behavior

Year:

1993

Language:

english

File:

PDF, 892 KB

english, 1993

23

Effects of St-587 and prazosin on water maze and passive avoidance performance of scopolamine-treated rats

Tarja Puumala, Jouni Sirviö, Sirja Ruotsalainen, Paavo Riekkinen Sr.

Journal:

Pharmacology Biochemistry and Behavior

Year:

1996

Language:

english

File:

PDF, 1.09 MB

english, 1996

24

The behavioral effects of serotonin synthesis inhibition and quisqualic acid induced lesions of the nucleus basalis magnocellularis in rats

Pekka Jäkälä, Maria Mazurkiewicz, Jouni Sirviö, Paavo Riekkinen Sr, Paavo Riekkinen Jr

Journal:

General Pharmacology: The Vascular System

Year:

1993

Language:

english

File:

PDF, 690 KB

english, 1993

25

Effects of NMDA receptor modulation on hippocampal type 2 theta activity in rats

Mervi Pitkänen, Jouni Sirviö, Aarne Ylinen, Esa Koivisto, Paavo Riekkinen Sr

Journal:

General Pharmacology: The Vascular System

Year:

1995

Language:

english

File:

PDF, 500 KB

english, 1995

26

Hippocampal damage after injection of kainic acid into the rat entorhinal cortex

Riitta Miettinen, Tiina Kotti, Jarkko Tuunanen, Ari Toppinen, Paavo Riekkinen Sr., Toivo Halonen

Journal:

Year:

1998

Language:

english

File:

PDF, 1.89 MB

english, 1998

27

Dexmedetomidine Reduces Response Tendency, but Not Accuracy of Rats in Attention and Short-Term Memory Tasks

Sirja Ruotsalainen, Antti Haapalinna, Paavo J. Riekkinen SR., Jouni Sirviö

Journal:

Pharmacology Biochemistry and Behavior

Year:

1997

Language:

english

File:

PDF, 874 KB

english, 1997

28

Modulation of Vigilance and Behavioral Activation by Alpha-1 Adrenoceptors in the Rat

Tarja Puumala, Paavo Riekkinen SR., Jouni Sirviö

Journal:

Pharmacology Biochemistry and Behavior

Year:

1997

Language:

english

File:

PDF, 368 KB

english, 1997

29

Discrimination of Alzheimer patients responding to cholinesterase inhibitor therapy

K. Alhainen, P. J. Riekkinen Sr.

Journal:

Acta Neurologica Scandinavica

Year:

1993

Language:

english

File:

PDF, 711 KB

english, 1993

30

Long-term efficacy and cognitive effects of vigabatrin

A. Ylinen, R. Kälviäinen, P. J. Riekkinen Sr

Journal:

Acta Neurologica Scandinavica

Year:

1995

Language:

english

File:

PDF, 349 KB

english, 1995

31

EEG reactivity correlates with neuropsychological test scores in Down's syndrome

J. Partanen, H. Soininen, M. Könönen, R. Kilpeläinen, E.-L. Helkala, P. Riekkinen Sr

Journal:

Acta Neurologica Scandinavica

Year:

1996

Language:

english

File:

PDF, 488 KB

english, 1996

32

Long-Term Alterations in NMDA-Sensitive l-[3H]Glutamate Binding in the Rat Hippocampus Following Fimbria-Fornix Lesioning

H. Lahtinen, E. Korhonen, E. Castrén, R. Miettinen, A. Ylinen, P.J. Riekkinen Sr.

Journal:

Experimental Neurology

Year:

1993

File:

PDF, 684 KB

1993

33

Characterization of Target Cells for Aberrant Mossy Fiber Collaterals in the Dentate Gyrus of Epileptic Rat

Tiina Kotti, Paavo J. Riekkinen Sr., Riitta Miettinen

Journal:

Experimental Neurology

Year:

1997

Language:

english

File:

PDF, 1.12 MB

english, 1997

34

Enhancement of Intermediate-Term Memory by an Alpha-1 Agonist or a Partial Agonist at the Glycine Site of the NMDA Receptor

Raimo Pussinen, Sakari Nieminen, Esa Koivisto, Antti Haapalinna, Paavo Riekkinen Sr., Jouni Sirviö

Journal:

Neurobiology of Learning and Memory

Year:

1997

Language:

english

File:

PDF, 142 KB

english, 1997

35

Preservation of hippocampal NMDA receptors may be crucial for spatial learning after epileptic seizures in rats

H. Lahtinen, A. Ylinen, M. Hyvönen, R. Miettinen, P.J. Riekkinen Sr.

Journal:

Year:

1993

Language:

english

File:

PDF, 1.87 MB

english, 1993

36

Slowing of EEG in Parkinson's disease

Raija Soikkeli, Juhani Partanen, Hilkka Soininen, Ari Pääkkönen, Paavo Riekkinen Sr.

Journal:

Electroencephalography and Clinical Neurophysiology

Year:

1991

Language:

english

File:

PDF, 554 KB

english, 1991

37

α1-Adrenoceptor antagonist decreased α2-adrenoceptor antagonist-induced high voltage spindle suppression in adult and aged rats

Paavo Riekkinen Jr., Jouni Sirviö, Liisa Toivanen, Minna Riekkinen, Risto Lammintausta, Paavo Riekkinen Sr.

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 334 KB

english, 1993

38

The effects of NMDA receptor antagonists at anticonvulsive doses on the performance of rats in the water maze task

Aarne Ylinen, Mervi Pitkänen, Jouni Sirviö, Tiina Hartikainen, Juhani Sivenius, Esa Koivisto, Paavo J. Riekkinen Sr.

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 674 KB

english, 1995

39

Effect of α2-adrenergic drugs dexmedetomidine and atipamezole on extracellular amino acid levels in vivo

Pirjo Valtonen, Antti Haapalinna, Paavo Riekkinen Sr., Toivo Halonen

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 797 KB

english, 1995

40

Failure of carbamazepine to prevent behavioural and histopathological sequels of experimentally induced status epilepticus

Hannele Lahtinen, Aarne Ylinen, Ulla Lukkarinen, Jouni Sirviö, Riitta Miettinen, Paavo Riekkinen Sr.

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 562 KB

english, 1996

41

Habituation of auditory N100 correlates with amygdaloid volumes and frontal functions in age-associated memory impairment

H.S. Soininen, J. Karhu, J. Partanen, A. Pääkkönen, V. Jousmäki, T. Hänninen, M. Hallikainen, K. Partanen, M.P. Laakso, K. Koivisto, P.J. Riekkinen Sr.

Journal:

Physiology & Behavior

Year:

1995

Language:

english

File:

PDF, 879 KB

english, 1995

42

The association of apolipoprotein E polymorphism with memory: a population based study

Eeva-Liisa Helkala, Keijo Koivisto, Tuomo Hänninen, Matti Vanhanen, Kari Kervinen, Johanna Kuusisto, Leena Mykkänen, Y. Antero Kesäniemi, Markku Laakso, Paavo Riekkinen Sr.

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 332 KB

english, 1995

43

Vigabatrin protects against kainic acid-induced neuronal damage in the rat hippocampus

Toivo Halonen, Riitta Miettinen, Ari Toppinen, Jarkko Tuunanen, Tiina Kotti, Paavo J. Riekkinen Sr.

Journal:

Neuroscience Letters

Year:

1995

Language:

english

File:

PDF, 570 KB

english, 1995

44

Screening for amyloid beta precursor protein codon 665, 670671 and 717 mutations in Finnish patients with Alzheimer's disease

Seppo Helisalmi, Arto Mannermaa, Maarit Lehtovirta, Markku Ryynänen, Paavo Riekkinen Sr., Hilkka Soininen

Journal:

Neuroscience Letters

Year:

1996

Language:

english

File:

PDF, 318 KB

english, 1996

45

Memory functions in human subjects with different apolipoprotein E phenotypes during a 3-year population-based follow-up study

E.-L. Helkala, K. Koivisto, T. Hänninen, M. Vanhanen, K. Kervinen, J. Kuusisto, L. Mykkänen, Y.A. Kesäniemi, M. Laakso, P. Riekkinen Sr.

Journal:

Neuroscience Letters

Year:

1996

Language:

english

File:

PDF, 365 KB

english, 1996

46

Apolipoprotein E polymorphism in patients with different neurodegenerative disorders

Seppo Helisalmi, Katja Linnaranta, Maarit Lehtovirta, Arto Mannermaa, Outi Heinonen, Markku Ryynänen, Paavo Riekkinen Sr., Hilkka Soininen

Journal:

Neuroscience Letters

Year:

1996

Language:

english

File:

PDF, 343 KB

english, 1996

47

Enhancements of synaptic transmission, LTP and memory by pharmacological agents

J. Sirviö, M. Pitkänen, R. Pussinen, A. Haapalinna, P.J. Riekkinen Sr.

Journal:

International Journal of Psychophysiology

Year:

1997

Language:

english

File:

PDF, 120 KB

english, 1997

48

ApoE and memory in old age

H.S. Soininen, P.J. Riekkinen Sr

Journal:

International Journal of Psychophysiology

Year:

1997

Language:

english

File:

PDF, 140 KB

english, 1997

49

Correlates of memory in patients with alzheimer's disease and age-associated memory impairment: A spect study

E-L Helkala, J. Kuikka, T. Hänninen, M. Hallikainen, K. Koivisto, P. Riekkinen Sr

Journal:

International Journal of Psychophysiology

Year:

1997

Language:

english

File:

PDF, 267 KB

english, 1997

50

463 Neuropsychological correlations of EEG reactivity in alzheimer's disease

J. Partanen, H. Soininen, E.-L. Helkala, M. Kononen, P. Riekkinen Sr

Journal:

International Journal of Psychophysiology

Year:

1998

Language:

english

File:

PDF, 119 KB

english, 1998